Written by Jamie Stowe | Wednesday, 01 October 2008 | There are 6 comments
The Mayo Clinic in America has been studying the weight loss drug Reductil on a number of overweight and obese volunteers who have different genetic make ups and have come up with the fascinating observation that the drug works differently on those with different genes. The study which was carried out to the highest clinical standards using a placebo controlled, double blind randomised format evaluated the impact of different doses (10 mg and 15 mg) of Reductil along with behavioural therapy at four week, eight week and twelve week intervals.

When the researchers examined the data but they saw that individuals who had a particular pattern of genetic variations lost more weight than those patients who did not have these specific genetic variations. For example the first group lost an average of between 10lbs. and 12lb. over the twelve week period which was considerably more than the second group.
This research is extremely important because it shows that genetic makeup can have a statistically significant effect on the effectiveness of individual medicines. Millions of dollars are being poured into weight loss research worldwide and a larger proportion of research is now being devoted to the genetic causes of obesity as scientists come round to the idea that genes could be playing a greater part in the cause of obesity than previously thought.
The issue of whether genes lead to obesity is a controversial one as many obese people like to blame their genes for their weight problems when in fact the problem is more concerned with unhealthy eating and lack of exercise. At the same time however scientists say that they have been able to pinpoint specific genes which tend to be found far more often in people with weight problems and therefore the link cannot be ignored.
The weight loss medication Reductil is the world’s best selling appetite suppressant and if doctors will be able to identify which people respond better to it they could have even better results with the medication than have already been observed. Reductil is a prescription medication and should only be used after doctor’s consultation.

There are 6 comments on this article.
LYNN ROWLEY said:
I HAVE BEEN TAKING REDUCTIL FOR 3 WEEKS AND FIND THEM VERY GOOD. I USED TO EAT CHOCOLATE AND SIT ON A NIGHT TIME AND PIG OUT ON FOOD AND NOW I EAT VERY LITTLE. IM SURE IT IS THESE TABLETS THAT STOP ME CRAVING FOOD, ALTHOUGHT I STILL ENJOY EATING EVERYTHING IM EATING BUT IT IS HEALTHIER FOOD. I JUST HOPE I AM STILL IN THIS FRAME OF MIND IN A COUPLE OF MONTHS TIME, THEN I WILL KNOW ITS THE REDUCTIL THATS WORKING FOR ME.
bettina said:
I have taken reductil for one year have lost 22 kg but then it stop working and I stop taking them I have all 22 kg and more on my bady again after 2 years but redy to try again if somthing vill help me after the waight loss.
Jack said:
Bettina, don't give up....you can do it. Try taking reductil again, maybe a break away from them will let them work again. sometimes taking pills for a length of time reduces their effect, however stopping for a while and starting again can help. Which ever way you do it, do not give up YOU CAN DO IT!!1
karen said:
I have just started taking reductil after xenical which didn't work as its a high fat diet pill, i don't eat very much as it is but over the last four years i have gained 4 stone weighing 12 and half now, i have been dieting for years yo yo dieting and now im paying the price, my body has just shut down, im hopeing this drug my help me but again i don't eat very much, can anyone help me on this?
Amanda said:
I have to say that Reductil worked for me. it had an effect straight away and I have lost two stone so far. I am very happy with it. I double checked that it was the real thing and it passed the test.
Sarah said:
I have only been taking reductil for 4 days but they seem to be working. I don't feel as hungry and i have been eating alot less. The best thing is that I was a real chocaholic and now i don't want it. I did try it twice and I didn't get the 'feelgood' factor from the seratonin release because of the chemicals in the pills. It tasted nice but I just didn't want to finish it, my husband couldn't believe it!
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